Camptotheca acuminata (C. acuminata) Decne., belonging to the family of Nyssaceae, is a deciduous hardwood forest tree species that is native to China. This light-demanding species is distributed in the Yangtze River basin and southern China and usually grows in warm and humid valleys at the foot of mountain slopes. Camptothecin (CPT), which comprises natural secondary metabolites, is commonly extracted from C. acuminata. Due to the inhibition of topoisomerase and the antiretroviral activity, CPT showed prominent effects in anti-tumor and immune deficiency disease resistance, which is widely used in the treatment of gastric cancer, colorectal cancer, bladder cancer, and so on.

Year：2011

Institution：The Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College

Material: Beijing, China

Data link: http://www.herbal-genome.cn/index.php?m=content&c=index&a=show&catid=100&id=103