Swertia mussotii Franch., referred to as “Zangyinchen” in Chinese, is a well-known Tibetan medicinal plant. It has been commonly used for the treatment of liver and gallbladder diseases, such as hepatitis, cholecystitis and fatty liver. 

Pubulications:

Fan G, Luo W Z, Luo S H, et al. Metabolic discrimination of Swertia mussotii and Swertia chirayita known as “Zangyinchen” in traditional Tibetan medicine by 1 H NMR-based metabolomics[J]. Journal of pharmaceutical and biomedical analysis, 2014, 98: 364-370.

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Ephedra is one of the oldest medicinal plants known to humankind and consists of about 50 species mainly distributed in temperate and subtropical regions of Asia, Central and South America and Europe. Ephedra sinica (ES) is the primary species that has been utilized in traditional Chinese medicine for over 5 000 years. The stems of ES, known as Mahuang (MH), have been traditionally used to treat asthma, coughs, edema, and fever with anhydrosis. The roots of ES, called Mahuanggen (MHG), have long been used as potent antiperspirants.

Pubulications:

1.      Lv M, Chen J, Gao Y, et al. Metabolomics based on liquid chromatography with mass spectrometry reveals the chemical difference in the stems and roots derived from Ephedra sinica[J]. Journal of separation science, 2015, 38(19): 3331-3336.

2.      Meng-Ying L V, Jian-Bo S U N, Min W, et al. Comparative analysis of volatile oils in the stems and roots of Ephedra sinica via GC-MS-based plant metabolomics[J]. Chinese journal of natural medicines, 2016, 14(2): 133-140.

3.      Xin G Z, Hu B, Shi Z Q, et al. A direct ionization mass spectrometry-based approach for differentiation of medicinal Ephedra species[J]. Journal of pharmaceutical and biomedical analysis, 2016, 117: 492-498.

Details:

http://202.203.187.112/index.php?m=content&c=index&a=show&catid=100&id=169

Hippophaë species vary in their secondary metabolites spectra, which results in a variation in treatment and health care efficacies2, 14, 20, 21. In addition, different species and subspecies have their own specific outstanding properties, such as fruit quality, ease to harvest and process, and drought and cold resistance abilities, especially related to the treatment of various diseases.

Pubulications:

Liu Y, Fan G, Zhang J, et al. Metabolic discrimination of sea buckthorn from different Hippophaë species by 1H NMR based metabolomics[J]. Scientific Reports, 2017, 7.

Details:

http://202.203.187.112/index.php?m=content&c=index&a=show&catid=100&id=168

Pseudostellariae Radix (Taizishen in Chinese, PR) is an arid tuberous root of Pseudostellaria heterophylla (Miq.) Pax ex Pax et Hoffm (Caryophyllaceae). It is a type of staple traditional Chinese medicine which has the functions of strengthening the spleen, replenishing Qi, moistening lungs, and producing fluids. This medicinal herb is consumed clinically for its positive effects.

Pubulications:

Hua Y, Hou Y, Wang S, et al. Comparison of Chemical Compositions in Pseudostellariae Radix from Different Cultivated Fields and Germplasms by NMR-Based Metabolomics[J]. Molecules, 2016, 21(11): 1538.

Details:

http://202.203.187.112/index.php?m=content&c=index&a=show&catid=100&id=167

Platycodon grandiflorum, a species of herbaceous flowering perennial plant of the family Campanulaceae, has been used as a traditional oriental medicine for bronchitis, asthma, pulmonary tuberculosis, diabetes, hepatic fibrosis, bone disorders and many others similar diseases and as a food supplement.

Pubulications:

Shin J H, Ahn Y G, Jung J H, et al. Identification and Characterization of Diploid and Tetraploid in Platycodon grandiflorum[J]. Plant Foods for Human Nutrition, 2017, 72(1): 13-19.

Details: 

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The native plant Parastrephia Lucida (Meyen) Cabrera is a native shrub, commonly called Siputola, growing in the pre-cordillera and Altiplano in the North of Chile and Argentina. This species has been historically used in traditional medicine as an anti-inflammatory agent, to treat toothache. Furthermore, this plant showed some biological activities with potential health benefits such as acaricide, fungicide, bactericide and antioxidant activities.

Pubulications:

Echiburu-Chau C, Pastén L, Parra C, et al. High resolution UHPLC-MS characterization and isolation of main compounds from the antioxidant medicinal plant Parastrephia lucida (Meyen)[J]. Saudi Pharmaceutical Journal, 2017.

Details: 

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The various species of Cirsium, which are members of the Compositae family, have been used for many years both as a food source and as traditional herbal medicine in Asian countries. In particular, Cirsium chanroenicum and C. setidens have been used to treat diverse types of bleeding in traditional medicine. Additional biological activities have been reported for C. chanroenicum, including detoxification, fever reduction, and enhanced blood circulation. Cirsium setidens is known for its antioxidant and hepatoprotective effects, as well as its activity against nonalcoholic fatty liver disease. 

Pubulications:

Kim M S, Nam M, Hwang G S. Metabolic Alterations in Two Cirsium Species Identified at Distinct Phenological Stages using UPLC‐QTOF/MS[J]. Phytochemical Analysis, 2018, 29(1): 77-86.

Details: 

http://202.203.187.112/index.php?m=content&c=index&a=show&catid=100&id=164

Atractylodes macrocephala Koidz is a traditional Chinese herb medicine, and the Polysaccharide of Atractylodes macrocephala Koidz has been shown to have the ability to regulate the immune functions.

Pubulications:

Shan G S, Zhang L X, Zhao Q M, et al. Metabolomic study of raw and processed Atractylodes macrocephala Koidz by LC–MS[J]. Journal of pharmaceutical and biomedical analysis, 2014, 98: 74-84.

Details: 

http://202.203.187.112/index.php?m=content&c=index&a=show&catid=100&id=163

Panax ginseng is one of the most important medicinal plants in Asia. Triterpene saponins, known as ginsenosides, are the major pharmacological compounds in P. ginseng.

Pubulications:

1.      Zhang H M, Li S L, Zhang H, et al. Holistic quality evaluation of commercial white and red ginseng using a UPLC-QTOF-MS/MS-based metabolomics approach[J]. Journal of pharmaceutical and biomedical analysis, 2012, 62: 258-273.

2.      Lee D Y, Kim J K, Shrestha S, et al. Quality evaluation of Panax ginseng roots using a rapid resolution LC-QTOF/MS-based metabolomics approach[J]. Molecules, 2013, 18(12): 14849-14861.

3.      Mao Q, Bai M, Xu J D, et al. Discrimination of leaves of Panax ginseng and P. quinquefolius by ultra high performance liquid chromatography quadrupole/time-of-flight mass spectrometry based metabolomics approach[J]. Journal of pharmaceutical and biomedical analysis, 2014, 97: 129-140.

4.      Wang J R, Yau L F, Gao W N, et al. Quantitative comparison and metabolite profiling of saponins in different parts of the root of Panax notoginseng[J]. Journal of agricultural and food chemistry, 2014, 62(36): 9024-9034.

5.      Chen Y, Zhao Z, Chen H, et al. Chemical differentiation and quality evaluation of commercial Asian and American ginsengs based on a UHPLC–QTOF/MS/MS metabolomics approach[J]. Phytochemical analysis, 2015, 26(2): 145-160.

6.      Chen X J, Qiu J F, Wang Y T, et al. Discrimination of three Panax species based on differences in volatile organic compounds using a static headspace GC-MS-based metabolomics approach[J]. The American journal of Chinese medicine, 2016, 44(03): 663-676.

7.      Nguyen H T, Lee D K, Choi Y G, et al. A 1 H NMR-based metabolomics approach to evaluate the geographical authenticity of herbal medicine and its application in building a model effectively assessing the mixing proportion of intentional admixtures: A case study of Panax ginseng: Metabolomics for the authenticity of herbal medicine[J]. Journal of pharmaceutical and biomedical analysis, 2016, 124: 120-128.

8.      Qiu S, Yang W, Yao C, et al. Nontargeted metabolomic analysis and “commercial-homophyletic” comparison-induced biomarkers verification for the systematic chemical differentiation of five different parts of Panax ginseng[J]. Journal of Chromatography A, 2016, 1453: 78-87.

9.      Wang S, Bai H, Cai Z, et al. MALDI imaging for the localization of saponins in root tissues and rapid differentiation of three Panax herbs[J]. Electrophoresis, 2016, 37(13): 1956-1966.

10.  Liu J, Liu Y, Wang Y, et al. The integration of GC–MS and LC–MS to assay the metabolomics profiling in Panax ginseng and Panax quinquefolius reveals a tissue-and species-specific connectivity of primary metabolites and ginsenosides accumulation[J]. Journal of pharmaceutical and biomedical analysis, 2017, 135: 176-185.

Details: http://202.203.187.112/index.php?m=content&c=index&a=show&catid=100&id=162

Cistanches Herba (CH, Chinese name: Roucongrong), initially archived in Shen Nong's Chinese Materia Medica, has been extensively regarded as one of the most well-known edible tonic and medicinal plants, and honored as “Ginseng of the deserts”. As one of the two official source plants of CH, Cistanche deserticola (CD, Orobanchaceae) is a holoparasitic plant and mainly distributed in the north and northwest of China. It has been widely utilized for the treatments of kidney deficiency characterized by impotence, pain in the loins and knees, female sterility, and constipation in traditional Chinese medicinal practices for centuries.

Pubulications:

1.      Song Y, Song Q, Li J, et al. An integrated strategy to quantitatively differentiate chemome between Cistanche deserticola and C. tubulosa using high performance liquid chromatography–hybrid triple quadrupole-linear ion trap mass spectrometry[J]. Journal of Chromatography A, 2016, 1429: 238-247.

2.      Zou P, Song Y, Lei W, et al. Application of 1H NMR-based metabolomics for discrimination of different parts and development of a new processing workflow for Cistanche deserticola[J]. Acta Pharmaceutica Sinica B, 2017, 7(6): 647-656.

Details:

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