Ephedra sinica

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Ephedra is one of the oldest medicinal plants known to humankind and consists of about 50 species mainly distributed in temperate and subtropical regions of Asia, Central and South America and Europe. Ephedra sinica (ES) is the primary species that has been utilized in traditional Chinese medicine for over 5 000 years. The stems of ES, known as Mahuang (MH), have been traditionally used to treat asthma, coughs, edema, and fever with anhydrosis. The roots of ES, called Mahuanggen (MHG), have long been used as potent antiperspirants.


1.      Lv M, Chen J, Gao Y, et al. Metabolomics based on liquid chromatography with mass spectrometry reveals the chemical difference in the stems and roots derived from Ephedra sinica[J]. Journal of separation science, 2015, 38(19): 3331-3336.

2.      Meng-Ying L V, Jian-Bo S U N, Min W, et al. Comparative analysis of volatile oils in the stems and roots of Ephedra sinica via GC-MS-based plant metabolomics[J]. Chinese journal of natural medicines, 2016, 14(2): 133-140.

3.      Xin G Z, Hu B, Shi Z Q, et al. A direct ionization mass spectrometry-based approach for differentiation of medicinal Ephedra species[J]. Journal of pharmaceutical and biomedical analysis, 2016, 117: 492-498.